Evidence for a signal peptide at the amino‐terminal end of human mitochondrial aldehyde dehydrogenase

[摘要]

A full-length cDNA clone coding for human mitochondrial aldehyde dehydrogenase (ALDH 1) was isolated from a human fetal muscle cDNA library. Sequence analysis revealed structural similarities between the amino-terminal end of ALDH I and other known targeting sequences responsible for protein uptake into the mitochondria.

[学科分类] 生物化学/生物物理

[关键词] Leader peptide;cDNA sequence;Aldehyde dehydrogenase I;(Human)