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A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family 1
[摘要]

A protein of unknown function has been identified as a key serological tool for diagnosis of human tapeworm neurocysticercosis, a major worldwide neurological disease. Our own sequence analysis predicts that this protein is a member of a newly identified cestode specific oligomeric hydrophobic ligand binding protein family. In this report, using a rat cestode model, we confirm that homologues of this protein can bind fatty acids and their derivatives, and thus suggest a biological function for this key diagnostic tool.

[发布日期]  [发布机构] 
[效力级别]  [学科分类] 生物化学/生物物理
[关键词] Hydrophobic ligand binding protein;Cestoda;Diagnosis;Hymenolepis diminuta [时效性] 
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