Paramagnetic metalloporphyrins as potential contrast agents in NMR imaging

[摘要]

Several water-soluble paramagnetic metalloporphyrins were found to increase significantly the relaxation rate (1/T ₁) of water. Such compounds are known to be selectively retained by tumors in animals, and consequently we identify them as potential contrast agents for tumors in NMR imaging.

[学科分类] 生物化学/生物物理

[关键词] Metalloporphyrin;NMR imaging;Paramagnetic reagent;NMR contrast agent