Blood group H antigen with globo‐series structure

[摘要]

Blood group H antigen with globo-series structure, reacting with the monoclonal antibody MBrl, was isolated and characterized from human blood group O erythrocytes. The structure was identified by methylation analysis, direct probe mass spectrometry, and ¹H-nuclear magnetic resonance spectroscopy as shown below: Fucαl → 2Galβl → 3GalNAcβl → 3Galαl → 4Galβl → 4Glcβl → 1Cer

[学科分类] 生物化学/生物物理

[关键词] Blood group H antigen;Globo-series structure;HPLC;high performance liquid chromatography;HPTLC;high performance thin-layer chromatography;NMR;nuclear magnetic resonance. Glycolipids are abbreviated according to the recommendations of the Nomenclature Committee;IUPAC [13];but the suffix ‘OseCer’ is omitted