Biochemical ethanol effects affected by a non‐steroidal anti‐inflammatory drug

[摘要]

The non-steroidal anti-inflammatory drug, piroxicam, prevents the hepatic increase of triacylglycerols and malondialdehyde resulting from the acute intoxication of rats with ethanol. In addition, in the intoxicated rats, piroxicam consistently produces a decrease in the levels of blood ethanol in comparison with control animals. It is suggested that the anti-inflammatory compound stimulates ethanol oxidation.

[学科分类] 生物化学/生物物理

[关键词] Ethyl alcohol;Alcoholic intoxication;Non-steroidal anti-inflammatory agent;Alcoholic hepatitis;Malonates;Piroxicam;NSAID;non-steroidal anti-inflammatory drug;MDA;malondialdehyde;TAG;triacylglycerides;OGV;orogastric via;IPV;intraperitoneal via