Imaging domains in model membranes with atomic force microscopy

[摘要]

Lateral segregation in biomembranes can lead to the formation of biologically functional domains. This paper reviews atomic force microscopy studies on domain formation in model membranes, with special emphasis on transbilayer asymmetry, and on lateral domains induced by lipid–lipid interactions or by peptide–lipid interactions.

[学科分类] 生物化学/生物物理

[关键词] Model peptides;Supported lipid bilayers;Phase separation;Rafts