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NADPH:O2 oxidoreductase of human eosinophils in the cell‐free system
[摘要]

The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.

[发布日期]  [发布机构] 
[效力级别]  [学科分类] 生物化学/生物物理
[关键词] Eosinophil;NADPH oxidase;Cell-free system;CGD.chronic granulomatous disease;Hepes;N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid;PMA;phorbol myristic acid;STZ;serum-treated zymosan;Moab;monoclonal antibody;Xb−;X-linked cytochrome b 558-negative;Ab+;autosomal cytochrome b 588-positive [时效性] 
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