Evidence that the α2HS glycoprotein receptor and the Epstein‐Barr virus nuclear antigen (EBNA) are identical

[摘要]

Evidence is presented which suggests that the α₂HS glycoprotein (α₂HS) receptor on lymphocytes transformed by Epstein—Barr virus (EBV) and the EBV-determined nuclear antigen (EBNA) are immunologically related, and may be identical. Western blotting, using both anti-EBNA and anti-α₂HS receptor serum identified a similar M _r 48 000 component in labelled detergent-solubilized transformed cell supernatants. The M _r 48 000 component recognized by anti-EBNA serum had a pI between 7–8, similar to that reported for the α₂HS receptor.

[学科分类] 生物化学/生物物理

[关键词] α2HS glycoprotein receptor;Epstein—Barr virus;Epstein—Barr virus nuclear antigen (EBNA);Lymphocyte