Is It Time to Evolve Past the Prerenal Azotemia versus Acute Tubular Necrosis Classification?

[摘要] For more than 70 years, the cornerstone for the diagnosis and management of acute kidney injury (AKI) has been the paradigm wherein its etiologies have been broken down into categories of prerenal, intrinsic, and postrenal disease (1). With postrenal obstruction usually readily apparent, the critical diagnostic distinction has typically been between prerenal and intrinsic causes, specifically acute tubular necrosis (ATN). Since the advent of nephrology as a discipline, the dichotomization of prerenal azotemia (PRA) and ATN has been a shibboleth of the renal community.

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome