Sleep Apnea in Individuals with Chronic Kidney Disease: A Wake-up Call

[摘要] Obstructive sleep apnea (OSA) is characterized by transient, repetitive partial or complete upper airway obstruction during sleep associated with sleep disturbance and chronic intermittent hypoxia (CIH). One in five Americans may have OSA, defined as an apnea-hypopnea index (AHI) of ≥5 events/h (1). Male gender and obesity are strongly associated with the presence of OSA. Importantly, most individuals (approximately 80%) with clinically significant OSA have not received a diagnosis (2). Recently, clinical guidelines recommending the incorporation of OSA into routine health evaluations with subsequent comprehensive sleep evaluation if OSA is suspected have been published (3). Individuals included as “high risk” for OSA include those with diabetes and hypertension who are also at increased risk for chronic kidney disease (CKD).

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome