Best Option for Transplant Candidates with Type 1 Diabetes and a Live Kidney Donor: A Bird in the Hand is Worth Two in the Bush

[摘要] For patients with type 1 diabetes complicated by ESRD, kidney transplantation prolongs life and frees the recipient from the substantial morbidities of dialysis. Live-donor kidney transplant (LDKT) and simultaneous pancreas-kidney transplant (SPKT) offer distinct benefits over receiving a deceased-donor kidney transplant (DDKT) alone. When a transplant physician is counseling a patient who has type 1 diabetes and ESRD and has a live donor, the decision about whether to proceed with LDKT or to remain on the waiting list for an SPKT requires careful consideration. The retrospective study by Young et al. (1) in this issue of CJASN provides an updated look at posttransplantation outcomes that illustrates the relative advantages of LDKT versus SPKT. Their findings support the adage that a bird in the hand may be worth two in the bush.

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome