Long-Term Outcome of Children with Steroid-Sensitive Idiopathic Nephrotic Syndrome

[摘要] In children, the most frequent glomerular disease is idiopathic nephrotic syndrome, which is defined by the combination of a nephrotic syndrome and nonspecific histologic abnormalities of the kidney including minimal changes, FSGS, and diffuse mesangial proliferation. The term minimal-change disease has become synonymous with steroid-sensitive idiopathic nephrotic syndrome, although renal biopsy is usually not performed for patients who respond to steroid therapy. Indeed, the response to steroid therapy carries a greater prognostic weight than the histologic features seen on initial renal biopsy.

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome