Initiation of Dialysis at Higher Levels of Estimated GFR and Subsequent Withdrawal

[摘要] Over the last 10–15 years, there has been a pervasive trend toward initiation of chronic dialysis at higher levels of estimated GFR (eGFR) across a range of different patient groups and practice settings (1–5). This finding seems to suggest that on average patients are now initiating chronic dialysis substantially earlier in the course of their kidney disease than in previous years (3). In light of recent trial evidence demonstrating that earlier initiation of dialysis at higher levels of eGFR does not lead to improved outcomes (6), these findings have helped to focus a spotlight on contemporary dialysis initiation practices (7⇓–9).

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome