Protecting the Microvasculature: A Tie-ght Connection to Ameliorating Chronic Kidney Disease?

[摘要] Chronic kidney disease (CKD) results from diverse etiologies, including glomerulonephritis, diabetes, and hypertension (1). The incidence of CKD is increasing worldwide and is predicted to reach epidemic proportions over the next decade (1). Current therapeutic strategies are based on the control, either by lifestyle modification or by pharmacologic intervention, of known risk factors (1), but there is clear need for new approaches and the development of effective therapies presents a major challenge.

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome