The Downside of a Drug-Crazed World

[摘要] In a world where patients are exposed to countless prescription drugs, it is amazing that more humans do not develop autoimmune drug reactions that lead to tissue injury. Of course, the chance of drug-related inflammation rises in proportion to use, but it still seems most of us are comfortably protected from such events by the high activation threshold of our immune systems. Genetic polymorphisms that modulate the initiation of antigen-specific immune responses, particularly in the MHC, are a determining influence, but the whole story is more complicated.

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome