Acute Kidney Injury: Toward an Integrated Understanding through Development of a Research Agenda

[摘要] Acute kidney injury (AKI) is widely recognized as an important predictor of morbidity and mortality and as an antecedent to chronic kidney disease (1). In the past 5 yr, there has been increasing interest in understanding this entity, at the both basic science and clinical levels. Recent advances in methodology have led to the description of both serum and urine biomarkers and the imaging of events occurring at the cellular level (2–5). Advances in understanding of and technology associated with dialysis in acute care settings have also contributed to the increasing recognition and treatment of AKI in these settings and the development of research studies to define its appropriate use (6–9).

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome