Venous Thromboembolism and Membranous Nephropathy: So What's New?

[摘要] The association of venous thromboembolism (VTE) with the nephrotic syndrome, particularly deep vein and renal vein thrombosis (DVT and RVT, respectively) is firmly established (1–3). In a retrospective study of 298 nephrotic patients followed for a mean period of 10 years (4), the annual incidence of VTE was 1.02%/yr, and the absolute risk of arterial thrombosis was 1.48%/yr. The risk of both venous and arterial thrombosis was particularly high within the first 6 months of diagnosis (with annual incidences of 9.85% and 5.52%, respectively) (4). In children with the nephrotic syndrome, 9.2% of 326 patients experienced 38 thromboembolic episodes over a median period of 3.7 years (5). This risk is particularly high in patients with idiopathic membranous nephropathy.

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome