Subgroup Analyses in Nephrology Clinical Trials

[摘要] There are various experimental designs available for evaluating the effectiveness of medical interventions. Although none are completely without limitations, the randomized controlled trial (RCT) is generally accepted as providing the most reliable evidence in the hierarchy of methodological options (1). The strength of well designed RCTs derives from limitation of bias through random allocation of patients to treatment groups and greater validity of statistical tests (2,3).

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome