Predicting Baseline Creatinine in Hospitalized Patients

[摘要] The confident evaluation of baseline kidney function is a fundamental component of any nephrology consultation. When abnormal kidney function is noted in a hospitalized patient, a clear sense of the patient's baseline is required to understand the relative acuity and/or chronicity of the process. Contemporary guidelines for the diagnosis and staging of AKI rely heavily on the ability to discern an incremental rise in serum creatinine above a baseline value within a fixed time frame (1–3). However, a standard definition for baseline creatinine does not exist, leading to heterogeneity across research studies (4) and the potential for misinterpreting the true nature of perturbed kidney function in hospitalized patients (5).

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome