Physical Activity in ESRD: Time to Get Moving

[摘要] Studies over the last 3 decades among ESRD patients on maintenance dialysis have demonstrated greatly impaired physical performance and cardiorespiratory fitness compared with the general population (1–4). Levels of habitual physical activity are also markedly lower in these patients. For example, Johansen et al. reported that among 34 maintenance hemodialysis patients, directly measured physical activity was nearly a third lower compared with healthy “sedentary” controls (5). Using data from the US Renal Data System (USRDS), Stack et al. reported that 56% of incident dialysis patients did not engage in any exercise, even once weekly (6). Accurate measurement of physical activity can be challenging in both ESRD patients and the general population. In large samples of participants, the most feasible technique is the use of questionnaires that ask about a range of potential physical activities that individuals may have engaged in within a fixed time period. “Gold-standard” measurement of physical activity relies on the use of a monitoring device worn at the waist or the leg that detects acceleration and records the duration and intensity of movement. The correlation between the self-reported questionnaires and directly measured activity varies widely but is often modest, including in renal disease patients (7).

[学科分类] 泌尿医学

[关键词] Bone marrow necrosis;Sickle cell disease;Hyperhemolysis syndrome