The main objective of this study is to assess the effect of strand anchorage on the behavior of prestressed concrete girders. Three AASHTO Type II girders with varying end anchorage details were tested. The results from these tests were compared with the results from previous experimental investigations (without end anchorage). The test results were also used to verify the tied-arch method, aimed at developing a rational prediction tool for determining the effect of anchorage on shear performance. The results from this investigation show that strand anchorage has a beneficial effect on the flexural, shear and ductility behavior of the girders. However, it was concluded that some transverse reinforcement is required to enable the modified system to perform in a consistently ductile manner and to avoid unfavorable failure modes in the end zones. Although the tied-arch model gives good correlation with the test results, it should not be used as a design tool.