The objectives of the instrumentation program were to measure and evaluate the behavior of a long span box girder bridge. Three bridge segments were instrumented. Field measurements were taken from the beginning of bridge construction for a total period of 5 years. Properties of concrete used in the instrumented segments were determined in the laboratory. Using the measured concrete properties and detailed construction records, time-dependent deformations of the bridge segments were calculated by a step-by-step numerical procedure. Calculated deformations were compared with measured data to verify the numerical procedure. Subsequently, the numerical procedure was used to determine information that could not be obtained by field measurements. Findings with regard to axial deformations, prestress losses, moment redistribution, concrete stresses, and temperature effects are presented.