The Study on Conformation and Biological Activity for the Drug Design. Phenethylamine Derivatives as the Sympathomimetics

[摘要] We applied the EHT method to 23 kinds of adrenergic agents, sympathomimetics, which were derived from phenethylamine by introducing hydroxy and methyl group to benzene ring, ¥á-or ¥â-position and nitrogen of ethylamine. We have stated and discussed theoretically the relationship between their structural characteristics and biological activities by compairing with the calculated values.

[学科分类] 化学（综合）