Reductive Amination of ,-Unsaturated Carbonyl Compounds with Tetracarbonylhydridoferrate as a Reducing Agent

[摘要] The reductive amination of three ¥á,¥â-unsaturated aldehydes, cinnamaldehyde, crotonaldehyde, and acrolein are carried out successfully by tetracarbonylhydridoferrate in the presence of various primary amines. In a typical reaction, a mixture of potassium tetracarbonylhydridoferrate (22 mmole), an amine (22¡­44 mole) and ¥á,¥â-unsaturated aldehyde (22 mmole), in ethanol (30¡­50 ml) was stirred for 9¡­60 hours at room temperature under carbon monoxide atmosphere. All the products were characterized as secondary amines by mass, infrared, and nmr spectra as well as gas chromatographic data.

[学科分类] 化学（综合）