Analysis of locoregional relapses from breast cancer

[摘要] Introduction: locoregional relapses after a breast cancer surgery is a big concern for the patient and a frustration to the performing surgeon. Objectives: to perform a descriptive study of the tumor recurrence-associated variables in 949 surgical patients.Methods: a database containing the data from operated patients in the period of 2005 through 2010 was made; the variables were identified and the univariate and multivariate analyses allowed determining the probable statistical association.Results: it was observed that the incidence of locoregional recurrence was 4.4 %. The most common previous surgery was modified radical mastectomy in 52.4 % and 26.2 % of cases with axillary ganglionic metastasis at that time. The most frequent histological type was highly malignant infiltrating bile duct carcinoma. The vascular and lymphatic infiltration occurred in 42.8 % of patients. The most used treatment was removal of recurrence plus radiotherapy. The multivariate analysis was associated only to ganglionic metastasis with the reappearance of disease.Conclusions: axillary ganglionic metastasis is still a factor indicating bad prognosis in the long follow-up of a patient.

[学科分类] 外科医学