The Kinetics and Mechanism of Nucleophilic Addition of Thioglycolic Acid to ¥â-Nitrostyrene Derivatives

[摘要] The rate constants of the nucleophilic addition of thioglycolic acid to the derivatives (H, p-CH3, p-CH3O, p-Cl, p-NO2) of �?-nitrostyrene were determined by ultraviolet spectrophotometry. The rate equations which can be applied over a wide pH range were obtained. Therefrom a reaction mechanism was proposed. Above pH 8.5 sulfide anion adds to the double bond (Michael type addtion). However, below pH 8.5, the neutral molecule and HSCH2COO- add to the double bond.

[学科分类] 化学（综合）