A In Vitro and In Vivo Study of the Ability of NOD1 Ligands to Activate the Transcriptional Factor NF-kB

[摘要] NF-kB �? nuclear factorkappa-light-chain-enhancer of activated B cells); AP-1 �? activator protein 1;TLR �? Toll-like receptor; PAMPs pathogen-associated molecular patterns; DAMPs �?damage-associated molecular patterns; PRR �? pattern recognition receptor; TNF-α�? tumor necrosis factor alpha; RT-PCR �? reverse transcription polymerase chain reaction;IRF �? interferon regulatory factor; NRL �? NOD-like-receptor; RLR �? RIG-likereceptors; LPS �? lipopolysaccharide.

[学科分类] 生物技术

[关键词] pattern-recognition receptors;Toll-like receptors;NOD1-receptor;transcriptional factor NF-kB;peptidoglycan of gram-negative bacteria.