Parameter estimation in arterial spin labeling MRI: Comparing the four phase model and the buxton model with fourier transform

[摘要] This paper presents a comparison between two algorithms that analyze and extract brain perfusion parameters from pulsedarterial spin labeling (ASL) MRI images. One algorithm is based on a Four Phase Single Capillary Stepwise (FPSCS) model,which divides the time course of the signal difference between the control and labeled images into four phases. The otheralgorithm utilizes the Buxton model and Fourier transformation (FTB). Both algorithms were implemented on MATLABto extract the bolus arrival time (BAT) and the cerebral blood flow (CBF). In-vivo brain MRI images acquired at 4T fromhealth volunteers were used in the comparison. Results indicated that the FTB algorithm had similar estimations of the BATand CBF compared to the FPSCS model when the time signals are sufficiently sampled, but the former had faster processingspeed while the FPSCS method provides additional information.

[学科分类] 外科医学

[关键词] Magnetic Resonance Imaging;Arterial Spin Labeling;bolus arrival time;cerebral blood flow