CT findings of a gastrointestinal stromal tumor arising from small bowel

[摘要] Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the gastrointestinal tract, arise from interstitial cells of Cajal. Most of them are composed of spindle cells and mimic leiomyoma morphologically. Nearly all GISTs demonstrate positive staining for CD-117 at immunohistochemistry examination, which helps to distinguishthem from true leiomyomas. We describe the CT findings of a GIST of small bowel. At plain CT scan, the tumor was ofhomogeneous iso-attenuation. After intravenous administration of contrast materials, a well-defined exophytic growth masswith avid homogeneous enhancement was demonstrated. The mucosal layer over the mass was intact and fat plane between the mass and adjacent GI wall was preserved. A diagnosis of GIST was suggested and was then confirmed by positivestaining for CD-117.

[学科分类] 外科医学

[关键词] Gastrointestinal stromal tumors;CD-117;CT findings