Injectable thermoreversible hyaluronan-based hydrogels for nucleus pulposus cell encapsulation

[摘要] Thermoreversible hydrogels have potential in spine research as they provide easy injectability and mild gelling mechanism (by physical cross-link). The purpose of this study was to assess the potential of thermoreversible hyaluronan-based hydrogels (HA-pNIPAM) (pNIPAM Mn = 10, 20, 35 × 103 g mol−1) as nucleus pulposus cells (NPC) carrier.

[学科分类] 骨科学

[关键词] Thermoreversible hydrogel;Hyaluronic acid;Nucleus pulposus;Hyaluronan synthase