Evaluation of the in vitro cell-material interactions and in vivo osteo-integration of a spinal acrylic bone cement

[摘要] Polymethylmethacrylate bone cements have proven performance in arthroplasty and represent a common bone filler, e.g. in vertebroplasty. However, acrylic cements are still subject to controversy concerning their exothermic reaction and osteo-integration potential. Therefore, we submitted a highly filled acrylic cement to a systematic investigation on the cell-material and tissue-implant response in vitro and in vivo.

[学科分类] 骨科学

[关键词] Acrylic bone cement;Osteo-integration;In vitro;In vivo implantation study;Bone marrow mesenchymal stem cells