We present a review of the geographic distribution of Cestrum mortonianum, as well as a description and an illustration of a new variety from the Sierra de Manantlan. The features that differentiate this variety from C. mortonianum var. mortonianum, and from C. tomentosum and C. pacificum all of which share the presence of branched pubescence are also discussed. A key to distinguish the Mexican species of Cestrum whith this indumenta is provided.