A preliminary phylogenetic analysis with nuclear ribosomal internal transcriber spacers (nrITS) sequence supports Muellera as a monophyletic group, sister of the genus Dahlstedtia, both groups sisters of Lonchocarpus. Thirteen species of Muellera from Mesoamerica and north of South America were studied. The nomenclature of Lonchocarpus to Muellera underwent three changes. Three new species are described to science: Muelleraamazonica, M. burkartii and M. chocoensis. M. frutescens, M. tubicalyx and M. unifoliolata are also described and illustrated. A dichotomous key is presented to compare the differences between species.
