Virulence factors in Aeromonas strains isolated from patients with acute diarrheas in Cuba

[摘要] Objective: A study was carried out in Aeromonas strains isolated from patients with acute diarrheas in Cuba to find out the phenotypical expression of the cytotoxin and the enterotoxin as virulence factors.Methods: Forty six strains of the genus Aeromonas (A. hydrophila, A. veronii bv sobria, A. caviae, A. veronii bv veronii and Aeromonas spp.) isolated from stool specimens taken form patients with acute diarrheal disease were studied from 2005 to 2006. All the strains had their pattern of antimicrobial susceptibility pattern identified. The phenotypic expression of the cytotoxin and the enterotoxin in the Vero cell line was checked.Results: It was demonstrated that 91,31 % of the strains showed cytotoxic activity and 43,48 % of them enterotoxic activity. Regarding multiresistant strains, 93,75 % presented with at least one of the studied virulence factors.Conclusions: these results proved that the two researched virulence factors did exist in the studied strains, thus contributing to the many efforts that are being made to learn about the mechanisms of enteropathogenicity of this bacterial genus.

[学科分类] 传染病学

[关键词] : Aeromonas;cytotoxicity;enterotoxigenicity