Genetic Analysis of an H5N2 Highly Pathogenic Avian Influenza Virus Isolatedfrom a Chicken in a Live Bird Market in Northern Vietnam in 2012

[摘要] References(14)Cited-By(3)In August 2012, A/chicken/Vietnam/OIE-2215/2012 (H5N2) was isolated from achicken in a live bird market (LBM) in Northern Vietnam. Intravenous pathogenicity testrevealed that this virus is highly pathogenic in chickens. The PA, HA, NP and M, PB2 andNA, and PB1 and NS genes of the isolate were phylogenetically closely related to those ofA/duck/Vietnam/OIE-2202/2012 (H5N1) of clade 2.3.2.1, A/chicken/Vietnam/OIE-1611/2012(H9N2) and A/chicken/Vietnam/OIE-2468/2012 (H9N2), respectively. All of these viruses wereisolated from birds in LBMs in the same province. These results indicate thatA/chicken/Vietnam/OIE-2215/2012 (H5N2) is a genetic reassortant and that surveillance ofavian influenza in LBMs and stamping out policy are essential for the eradication ofhighly pathogenic avian influenza viruses from Asia.

[学科分类] 兽医学

[关键词] avian influenza;H5N2;live bird market;reassortant;Vietnam