Herpes Simplex Virus Type 1 Infection in Two Pet Marmosets inJapan

[摘要] References(17)Cited-By(1)An 8-month-old common marmoset (Callithrix jacchus) was presented with tic-like symptoms, and a 2-year-old pigmy marmoset (Callithrix pygmaea) was presented with dyspnea and hypersalivation. Both monkeys died within a few days, and necropsies were performed.Histopathological examinations revealed ulcerative stomatitis with epithelial cellswelling and eosinophilic intranuclear inclusion bodies in the oral epithelium of bothcases. In the central and peripheral nervous systems, neuronal cell degeneration withintranuclear inclusion bodies was observed. Immunohistochemical examination usinganti-herpes simplex virus type 1 antibody revealed virus antigens in both cases. Bothanimals had been kept as pets with limited exposure to the ambient environment except viatheir owners. Therefore, herpes simplex virus type-1 was probably acquired from closecontact with their owners.

[学科分类] 兽医学

[关键词] herpes virus;marmoset;zoonosis