Seroepidemiology of Reovirus in Healthy Dogs in Six Prefectures inJapan

[摘要] References(33)Cited-By(1)Reovirus infection is common in mammals. However, seroepidemiological data ofreovirus neutralizing antibodies are limited in dogs. In this study, sera of 65 healthydogs from six prefectures across Japan were tested for neutralizing antibodies againstreovirus serotype 1 strain Lang (T1L), serotype 2 strain Amy (T2A) and serotype 3 strainDearing (T3D) using plaque reduction neutralization test (PRNT). Seropositivity againstreovirus T1L, T2A and T3D was 53.85%, 33.85% and 46.15%, respectively. Distribution ofreovirus seropositive samples displayed no distinguishable geographical pattern. However,reovirus seropositivity increased with age and in dogs housed outdoor. Co-infection ofmultiple reovirus serotypes in dogs was also detected. These data will provide valuableinsights towards the usage of reovirus in oncolytic virotherapy in canine cancers.

[学科分类] 兽医学

[关键词] canine;neutralizing antibody;plaque reduction neutralization test;reovirus;seroepidemiology