Immunocytochemical Localization of Desmin in Skeletal Muscle of Swine

[摘要] References(16)Cited-By(2)A porcine antibody was used to clarify the localization of desmin filaments in the swine longissimus muscle by post-embedding immuno-electron microscopy. The major site of desmin localization was the bundle of filaments connecting Z-discs of adjacent myofibrils. These desmin filaments were localized not only between but also within myofibrils. This indicates that there exist more complicated networks rather than simple bundles of desmin filaments running parallel to the Z-discs. Clarification of desmin distribution within the myofibrils surrounding Z-discs provides a basic concept for consideration of the combination and transformation of vimentin to desmin in developing human embryonic muscles.

[学科分类] 兽医学

[关键词] desmin;immunocytochemistry;Post-embedding method;swine;Z-disc