Disinfestation of Experimentally Infested Cat Fleas, Ctenocephalides felis, on Cats and Dogs by Oral Lufenuron

[摘要] References(19)In vivo efficacy of orally administered lufenuron, an insect growth regulator, in disinfesting cat fleas was evaluated, using flea-free cats and dogs which were purchased and infested every 10 days with cat fleas from a colony kept in our laboratory. Lufenuron was orally administered as a single dose of 15, 30, or 60 mg/kg to cats, and 5, 10 or 20 mg/kg to dogs. In cats, adult flea emergence was intensively prevented for 30 days by dosing of 15 mg/kg of lufenuron and 40 days by 30 or 60 mg/kg. The average egg hatch rate in 15mg/kg group was, however, significantly higher than those in 30 mg/kg or more, suggesting necessity to dose 30 mg/kg to cats to prevent development of cat fleas effectively. In dogs, a lower dose of the drug, 10 mg/kg seemed to be sufficient for the complete prevention of flea development.

[学科分类] 兽医学

[关键词] cat flea;Ctenocephalides felis;flea disinfestation;lufenuron