Glomus tumor of the liver in a cow

[摘要] References(25)An 11-year-old Holstein-Friesian cow exhibited anorexia and jaundice. A large mass wasfound in the liver during necropsy. Macroscopically, the mass was composed of dark redmultilobular tissue and a centrally located abscess, which was connected to the hepaticduct. Histologically, the mass consisted of proliferation of small neoplastic cells andwas demarcated from the hepatic parenchyma by a thick region of granulation tissue. Theneoplastic cells were predominantly arranged in solid sheets, but they also formedblood-filled cancellous structures, and proliferating foci were seen around blood vessels.Periodic acid-Schiff reaction demonstrated that a fine basement membrane-like structuresurrounded the neoplastic cells. Immunohistochemically, the neoplastic cells were positivefor vimentin and alpha smooth muscle actin and negative for cytokeratin, factorVIII-related antigen, chromogranin and desmin. Based on its histopathological features,the hepatic neoplasm was diagnosed as a primary glomus tumor. This is the first reportabout a primary glomus tumor of the liver in a cow.

[学科分类] 兽医学

[关键词] cholangitic abscess;cow;glomus tumor