Surveillance of avian paramyxovirus serotype-1 in migratory waterfowls inJapan between 2011 and 2013

[摘要] References(19)Cited-By(1)To further understand the epidemiology of avian paramyxovirus serotype-1 (APMV-1) inmigratory waterfowls in Japan, we conducted the surveillance of this virus from fecesderived from the migratory waterfowls collected in 41 Japanese prefectures between October2011 and March 2013. Six APMV-1 viruses were isolated from total 661 samples. All isolateswere identified as the avirulent (lentogenic) type on the basis of intracerebralpathogenicity tests. Genetic analysis showed that these viruses possessed the deducedamino acid sequence of 112GKQGR-L117 or112ERQER-L117 at the cleavage site of the F0 protein, which wasidentical to the motif in the avirulent type. Phylogenetic analysis based on the partialfusion protein gene classified these APMV-1 isolates into 2 major genetic groups. Fourisolates were classified as class II genotype I, and they were genetically closely relatedto strains isolated in Asian countries, including Japan. In contrast, two isolates wereclassified as class I, and they were genetically closely related to strains mainlyisolated in the U.S.A.

[学科分类] 兽医学

[关键词] avian paramyxovirus type 1;genotype;phylogeny