Lymphangiosarcoma with systemic metastases in a Japanese domesticcat

[摘要] References(25)A 4-year-2-month-old female Japanese domestic cat was diagnosed with lymphangiosarcomathrough tissue biopsy of an amputated leg. Two months later, the cat was euthanized, andpostmortem findings revealed edema, and bruising at the caudal region of the trunk,pulmonary hemorrhage, pulmonary nodules and mediastinal lymphadenopathy. Microscopically,neoplastic tissues were observed in the dermis and subcutis of the trunk, lung,mediastinal lymph nodes, diaphragm, omentum and mesentery. The tumor cells were spindle topolygonal-shaped with nuclear pleomorphism aligning along pre-existing collagen bundlesand forming irregular vascular channels in which the erythrocytes were rarely observed.These cells were immunopositive for vimentin, von Willebrand factor and CD31. Based on thehistopathological and immunohistochemical features, the neoplasia was diagnosed aslymphangiosarcoma with systemic metastases.

[学科分类] 兽医学

[关键词] feline;lymphangiosarcoma;metastases