Comparative Analysis of the Putative Amino Acid Sequences of Chlamydial Heat Shock Protein 60 and Escherichia coli GroEL

[摘要] References(19)Cited-By(4)The nucleotide sequences of the gene encoding chlamydial heat shock protein 60(cHSP60)of 7 Chlamydia psittaci strains were determined.Comparison of sequences of the cHSP60 gene among chlamydiae showed high identities of the nucleotide sequences by 81.0% or greater and of the deduced amino acid sequences by 92.2% or greater.Comparison of the amino acid sequences between chlamydia and the other bacterial HSP60s resulted in the finding of three highly conserved regions, suggesting that these regions play a role in some function.In addition, 26− or 27−functional residues in the Escherichia coli GroEL out of the 28−residues are conserved in the amino acid sequences of the cHSP60.The data suggest that the function of the cHSP60 may be the same as that of the E.coli GroEL.

[学科分类] 兽医学

[关键词] Chlamydia psittaci;HSP60;nucleotide sequence