Myeloblastic Leukemia with Massive Neoplastic Infiltration of the Skin and Mediastinum in a Cow

[摘要] References(26)Cited-By(2)An acute myeloblastic leukemia was found in a 3.5-year-old Holstein cow. The neoplasm was characterized by massive tumor growths, and there were multiple tumor nodules in the dermis or subcutis and a large tumor mass in the mediastinum. This tumor showed negative reactivity for CD3, CD79a, major histocompatibility complex class II and myeloid/histiocyte antigen. Ultrastructural features such as dispersed cytoplasmic granules and poorly developed organelles were compatible with those of early promyelocytes.

[学科分类] 兽医学

[关键词] bovine;myeloblastic leukemia;skin