Canine IgA nephropathy: a case report

[摘要] References(11)Immunoglobulin (Ig) A nephropathy is a rare form of canine glomerular disease. Thisreport describes a case of canine IgA nephropathy showing characteristics typical of humanIgA nephropathy. An 8-year-old, spayed female Miniature Dachshund showed persistent severeproteinuria without azotemia. She was receiving long-term glucocorticoid therapy due tochronic gastritis and an intra-abdominal suture granuloma. A renal biopsy demonstratedmesangial proliferative glomerulonephritis with predominantly mesangial IgA deposition andelectron-dense deposits in the paramesangium. These findings closely resembled those ofhuman IgA nephropathy. Glucocorticoid treatment was discontinued, and theangiotensin-converting enzyme inhibitor enalapril was administrated as an antiproteinuricagent. The proteinuria subsequently went into remission, and the patient has maintainedgood condition without recurrence.

[学科分类] 兽医学

[关键词] angiotensin-converting enzyme inhibitor;canine;IgA nephropathy;proteinuria;renal biopsy