Second generation sequencing allows for mtDNA mixture deconvolution and high resolution detection of heteroplasmy

[摘要] Aim To use parallel array pyrosequencing to deconvolute mixtures of mitochondrial DNA (mtDNA) sequence and provide high resolution analysis of mtDNA heteroplasmy. Methods The hypervariable segment 1 (HV1) of the mtDNA control region was...

[学科分类] 卫生学