Epigenetic drug 5-azacytidine impairs proliferation of rat limb buds in an organotypic modelsystem in vitro

[摘要] Aim To establish an organotypic in vitro model of limb bud development to verify whether epigenetic drug and teratogen 5-azacytidine (5azaC) has an effect on limb buds independent of its effects on the placenta. Methods Fischer strain...

[学科分类] 卫生学