Historic Exposure to Plague and Present-day Frequency of CCR5del32 in Two Isolated Island Communities of Dalmatia, Croatia

[摘要] Aim: To assess the frequency of deletion of 32 base pairs in a CCR5 gene, shown to confer resistance to HIV infection, in two isolated island communities of Dalmatia, Croatia, with different histories of exposure to “plague�? during...

[学科分类] 卫生学

[关键词] CCR5del32;Croatia;isolated populations;plague;positive selection