Alternate Exon in the 5'-Untranslated Region of the Human ACTH Receptor Gene

[摘要] References(14)Cited-By(1)The human ACTH receptor (ACTH-R) gene consists of two exons; the first encodes the 5'-untranslated region (UTR) and the second encodes part of the 5'-UTR, the entire coding region, and the whole of the 3'-UTR. While investigating the transcription initiation site of the human ACTH-R gene by 5'-rapid amplification of cDNA ends, we found a 157-bp alternate exon in the 5'-UTR. This newly identified exon was irrelevant to the alternate exon in the mouse ACTH-R gene which we reported previously.

[学科分类] 内分泌与代谢学

[关键词] Gene structure;Alternative splicing;ACTH receptor;Adrenal gland;Human