AGO Recommendations for the Diagnosis and Treatment of Patients with Advanced and Metastatic Breast Cancer: Update 2014

[摘要] For the last 13 years, the Breast Committee of the Arbeitsgemeinschaft Gynäkologische Onkologie (German Gynecological Oncology Group, AGO) has issued annually updated evidence-based recommendations for the diagnosis and treatment of patients with early and metastatic breast cancer. The AGO Breast Committee consists of 45 gynecological oncologists specialized in breast cancer and interdisciplinary members specialized in pathology, radiological diagnostics, medical oncology, and radiotherapy. Each update is performed/assembled in accordance with documented rules, by thoroughly reviewing and scoring the recent publications chapter by chapter for their scientific validity (Oxford Level of Evidence, LoE; www.cebm.net [1]) and clinical relevance (AGO grades of recommendation; table ​table1).1). All AGO Breast Committee members have declared their potential conflicts of interest. Here, we present the 2014 update of these guidelines, focusing on relevant changes introduced this year. The full version of the updated 2014 slide set is available online as a PDF file [2], in English and German. Moreover, a version for patients is also available at www.ago-online.de.

[学科分类] 泌尿医学

[关键词] Guidelines;Locoregional relapse;Metastatic breast cancer;Targeted therapy